I know this general topic has been addressed, but I have a specific question about the use of packing cubes in the Synapse 25. I am a student and often travel home for the weekend. I also babysit overnight one night a week. I have been using my Synapse 25 for a mixture of books, toiletries, and clothing on these occasions, but not very efficiently and I find myself squeezed for space. Can anyone recommend a packing cube that would fit in the Synapse 25 to pack clothing (generally a pair of pajamas and one outfit of size small/4 women's clothing) smaller and to separate books from clothing? On these occasions, In addition to the clothing, I generally end up carrying one fairly typically sized textbook, a large notebook, a half inch binder, a cylindrical pencil case, one large organizer pouch full of paper, a medium organizer pouch with my macbook charger in it, a 13" macbook in a cache, and some other small items easily stuffed into pockets. Any organizational advice for this type of use besides for the use of a packing cube for clothing would be welcome. I have been trying to convince myself I don't need a Brain Bag for this purpose and am hoping someone here can help convince me. Heck, why not ask too if anybody thinks there's a good way to use the Aeronaut instead. I think it's really too big and really not the ideal layout for books, but maybe others here have found interesting ways to utilize its space.