I was fortunate enough to get picked by The Great and Terrible Countron for one of the pre-production Synik 22s, and it came today. I've benefited so much from other people's reviews I thought I'd mention a few things I haven't seen specifically addressed elsewhere.
(tl;dr: It's as good as everyone says it is and you are correct to covet it.)
My primary points of comparison are older (Cordura) Synapses of both sizes, so some of the differences are no doubt things that have already found their way into the current Synapses. I haven't had much chance to do anything more than transfer my daily carry from the S19, so I can't speak to (for instance) how the straps feel over long distances.
Parapack
Normally I'd never buy a bag in black or blue, but I decided on black parapack and I don't regret it. A very sexy fabric. One downside (presumably shared by Halcyon) is that when the bag is packed tight you can see the distinct shapes of objects inside; e.g., when the lefthand front pocket is full, the outline of each individual pen in the pen loops is visible.
The unexpected upside is that since the lining is also parapack, the pocket in the main compartment now feels much stiffer and more like its own separate space instead of just a flap of fabric floating around. It's literally the same setup as the Halcyon pockets in my Synapses, but now the pocket feels like it has more integrity and will stay flatter if there's nothing in it. (Am I impugning the integrity of the Halcyon pocket divider? I MIGHT BE.)
As long as we're here in the main compartment ...
Clamshell
I used to have a Minaal Carry-On that was in many ways a wonderful bag, but one of the selling points was that the fabric was thin and light, which meant that there was no structure to the main compartment, which meant that when you opened the clamshell, even on a flat surface, things were always in danger of rolling away and getting lost under the trophy case. (A pretty compelling argument in favor of O-rings.)
So I was ambivalent about the clamshell, but when I opened the bag all the way, I noticed that in addition to protecting the zippers, the padded bottom panel is serving another function: it gives the main compartment structure. The top of the bag is still a little limp and tends to sag, but the bottom is holding both the sides up, so it feels like you're placing things into a compartment rather than just laying them on a piece of fabric at gravity's mercy.
Packing Straps
When I opened the main compartment I also noticed that even though the two white packing straps seem to be the same length, the bottom one is snug and flush against the laptop compartment, while the top one is a bit slack and droops down when you stand the bag up. I will not tell you how long it took me to figure out that this is because, duh, the top of the bag is narrower. (Hint: you would have had enough time to prepare and drink a hot beverage.)
I had been thinking I'd just leave the straps in the bag all the time, but in addition to looking kind of sloppy, the looseness of the top strap creates a hanging loop that is something of an obstacle to putting things in the bag. So out they go. I might try them when travelling, but I use packing cubes so I may not need them at all.
Front Pockets
The lower chin pocket feels significantly smaller than the same pocket in my S19. I keep two 3DOCs in there along with a ChicoBag Vita, and I had to get pretty western with them to make them fit in the Synik. I don't think they'd fit if they were full.
(EDIT: After Cristina posted below, I went back and tried both bags again, and while it did in fact feel smaller -- as in, I had to put a lot more effort into getting the stuff to fit in the Synik -- visually, the pockets are the same size. Not sure why it feels so much more difficult to pack the Synik, but maybe I am just a big weakling milk baby.)
On the other hand, as noted elsewhere, the new side pockets are yuuuge, so maybe it's just a case of rearranging where I put things.
I am a thirsti boi, so I typically carry a one-liter Camelbak Chute, and after seeing all the pictures of tuskegee7294's trip to World O' Water Bottles (thank you for your service, ma'am) I was convinced it wasn't going to fit in the SN22. Amazingly, it does. It's stealing a lot of capacity from the surrounding compartments, though, so I may still switch out to a bottle that isn't as desperate to be the center of attention.
Strap Holders
These are great. Better, IMHO, than either Web Dominators (which protrude too much) or Strapeez (which lack aesthetic flair). I'm a little worried that they'll slip off, but if they don't, they should become standard issue with every TB backpack. (Suggestion: include a second pair for the sternum strap.)
Label
I think the label looks badass on this bag, though I will admit that it works particularly well on the black, both because it blends in better and because the bag might seem a little blank without it. As Nathan Lane says in The Birdcage, one does want a hint of color.
On the other hand, TB uses fewer stitches on the label than they used to, which is good news for those of you planning to take a seam ripper to it.
Size
In practical terms it would have made more sense for me to get an SN30 to use as a travel bag and stick with my Synapses for everyday carry, but I believe I'm in the right room to admit that I didn't want to buy a Synik I was only going to get to use on trips. So I convinced myself that in addition to being my EDC, the SN22 would also work as a travel bag.
And it might. I pack pretty minimally, so I think I can get a travel cube in there in addition to my regular kit, but that's not going to leave much room for souvenir tchotchkes. I may wind up having to save up for an SN30 as well, and WOULDN'T THAT BE TERRIBLE.
In the meantime, I'm happy to see that even though the Synik looks a little squarish when flat, the more I put into it, the more it assumes that familiar and pleasingly pearish shape.
This will come as no surprise to anyone reading this, and it comes as no surprise to me, but this bag is beautifully designed and made and I'm completely delighted with it. And of course I'm thrilled I got it even earlier than I thought I would. Many thanks to the entire TB team for their predictably superior work in every department.
Here endeth the random thoughts. I didn't want to take pictures at night, but if you want to see a photo of some particular aspect of the bag let me know and I'll take some tomorrow.